Just want to mention an old eMachine tower that has Raring UPUP 3.9.9.2 that is running Apache 2.2 and MySQL 5.4 used as a gateway and reverse proxy has reached an uptime of 271 days.
There are 3 zoneminder servers each with a dedicated domain name and URL behind the machine plus other test and development servers also being directed to by the UPUP 3.9.9.2 machine.
this OS and machine combo has proven to be extremely stable and reliable.
the UPUP 3.9.9.2 OS I can highly recommend to serve in this capacity.
Long Live Puppy Linux!